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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SF3A1 All Species: 13.33
Human Site: T681 Identified Species: 26.67
UniProt: Q15459 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15459 NP_001005409.1 793 88886 T681 P P M E D E P T S K K L K T E
Chimpanzee Pan troglodytes XP_515067 793 88845 T681 P P M E D E P T S K K L K T E
Rhesus Macaque Macaca mulatta XP_001109090 793 88798 T681 P P M E D E P T S K K L K T E
Dog Lupus familis XP_534733 793 88764 A681 P P M E D E P A S K K L K T E
Cat Felis silvestris
Mouse Mus musculus Q8K4Z5 791 88526 P679 P P M E D E P P S K K L K T E
Rat Rattus norvegicus NP_001100705 791 88569 P679 P P M E D E P P S K K L K T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026643 791 88489 V678 P P M E D E P V S K K L K S E
Frog Xenopus laevis NP_001085709 802 90334 A690 P P L E D E P A A K K M K S E
Zebra Danio Brachydanio rerio NP_956388 780 87898 S668 P P H E D E P S S K K M K T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650583 784 88057 P673 D I M E E E P P S K K I R S E
Honey Bee Apis mellifera XP_393373 766 86238 Q654 E P M E E E P Q T K K L R T E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXF1 785 87576 E678 P P L P E E P E A K R Q K F D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.6 98.6 N.A. 98.1 98.1 N.A. N.A. 92.4 86.2 84.1 N.A. 52.4 58.1 N.A. N.A.
Protein Similarity: 100 99.7 99.7 99.2 N.A. 98.3 98.4 N.A. N.A. 95.4 92.3 91 N.A. 68 72.5 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 66.6 80 N.A. 53.3 66.6 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 93.3 93.3 N.A. 80 86.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 37 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 55.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 17 17 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 75 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 9 0 0 92 25 100 0 9 0 0 0 0 0 0 92 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 100 92 0 84 0 0 % K
% Leu: 0 0 17 0 0 0 0 0 0 0 0 67 0 0 0 % L
% Met: 0 0 75 0 0 0 0 0 0 0 0 17 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 84 92 0 9 0 0 100 25 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 9 0 17 0 0 % R
% Ser: 0 0 0 0 0 0 0 9 75 0 0 0 0 25 0 % S
% Thr: 0 0 0 0 0 0 0 25 9 0 0 0 0 67 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _